论文部分内容阅读
合成了苯基氨基甲酸酯衍生化 β-环糊精键合固定相 ,1 4个 α-氨基膦酸酯类化合物首次在该固定相和商品化的 ( S) -( +) -萘乙基氨基甲酸酯衍生化β-环糊精固定相上进行液相色谱手性拆分 .通过定量结构 -对映异构体保留关系对比研究了两种不同的环糊精类固定相上可能的色谱保留和手性识别机理
Phenylcarbamate derivatized β-cyclodextrin bonded stationary phase was synthesized. The first 14 α-amino phosphonates were separated on the stationary phase and commercially available (S) - (+) - naphthalene B Chiral Resolution by Liquid Chromatography on a Carbamate-Derivatized β-Cyclodextrin Stationary Phase. By means of quantitative structure-enantiomeric retention relationships, two different cyclodextrin-based stationary phases were investigated Chromatographic retention and chiral recognition mechanisms