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目的:提高对十二指肠间质瘤的临床特点、病理和免疫组织化学(免疫组化)及治疗方法的认识。方法:对报道1例十二指肠间质瘤的临床资料进行数理分析,并结合文献进行复习和讨论。结果:该例主要临床表现为腹痛、排黑便,上腹部CT、磁共振和胃镜检查均提示十二指肠肿瘤,行十二指肠肿瘤切除术,术后病理检查示十二指肠梭形细胞瘤,免疫组化结果示肿瘤细胞CD117 (+),CD34(+)。结合蛋白(-),S-100蛋白(-),肌动蛋白(-),最后确诊为十二指肠良性间质瘤。结论:十二指肠间质瘤临床少见,症状无特异性,主要依靠组织病理及免疫组化检查来确诊。免疫组化表型特征为CD117(+),CD34(+),治疗方法以手术切除为主。
Objective: To improve the clinical features of duodenal stromal tumors, pathology and immunohistochemistry (immunohistochemistry) and treatment of awareness. Methods: The clinical data of one case of duodenal stromal tumors were analyzed by mathematical analysis and reviewed with the literature. Results: The main clinical manifestations of this case were abdominal pain, melena row, upper abdominal CT, magnetic resonance and gastroscopy were prompted duodenal tumors, duodenal tumor resection, postoperative pathology showed the duodenum Astrocytoma, immunohistochemical results showed that the tumor cells CD117 (+), CD34 (+). Binding protein (-), S-100 protein (-), actin (-), the final diagnosis of benign duodenal stromal tumors. Conclusion: The duodenal stromal tumors are rare and the symptoms are nonspecific. The diagnosis is mainly based on histopathology and immunohistochemistry. Immunohistochemical phenotypic characteristics of CD117 (+), CD34 (+), the treatment of surgical resection based.