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[目的]探讨血清尿酸在不同性别的甲状腺功能亢进症（甲亢）中的表达及意义。[方法]选择我院2011年5月至2013年6月诊断为甲亢的门诊及住院患者90例作为观察组，另选择健康者90例作为对照组。观察两组游离甲状腺三碘原氨酸（FT3）水平及血清尿酸（UA）水平。[结果]观察组男性、绝经前及绝经后女性FT3水平均显著高于对照组（ P ＜0．05）；观察组男性、绝经后女性UA水平显著高于对照组（ P ＜0．05），两组绝经前妇女UA水平差异无统计学意义（ P ＞0．05）。观察组男性、绝经前妇女及绝经后妇女FT3水平与UA水平呈正相关（ P ＜0．05）。[结论]甲亢患者 UA水平相比正常对照组明显升高，加强对患者UA水平监测，对积极预防痛风及心血管病的发生具有重要意义。“,”[Objective] To explore the clinical significance of serum uric acid level in hyperthyroidism pa-tients with different sex .[Methods] Totally 90 outpatients and inpatients diagnosed as hyperthyroidism in our hospital from May 2011 to June 2013 were selected as the observation group .And 90 healthy people were se-lected as the control group .The levels of FT3 and serum uric acid of two groups were observed .[Results]FT3 levels of men ,premenopausal and postmenopausal women in observation group were markedly higher than those in control group( P <0 .05) .Serum uric acid levels of men ,premenopausal and postmenopausal women in observation group were markedly higher than those in control group ( P 0 .05) .The levels of FT3 in men ,premenopausal and postmenopausal women of observation group were positively correlated with serum uric acid levels ( P <0 .05) .[Conclusion] Compared with control group ,serum uric acid level in pa-tients with hyperthyroid is obviously increased .Strengthening the monitoring of serum uric acid level is impor-tant to actively prevent the occurrence of gout and cardiovascular disease .