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目的探讨诱发电位对单纯颈内动脉狭窄的临床诊断价值。方法选择30例经颈动脉超声并经颅脑CT或MRI证实排除脑梗死的单纯颈动脉狭窄的患者,并以30名正常健康老年人作对照,进行体感诱发电位(SEP)、脑干听觉诱发电位(BAEP)和脑干视觉诱发电位(VEP)的检测。结果颈动脉狭窄患者中,SEP异常率为40.0%,其各波潜伏期较对照组明显延长、波幅均较对照组明显升高;BAEP异常率为6.67%,其各波潜伏期较对照组无明显延长;VEP异常率为3.33%,其各波潜伏期较对照组无明显延长。结论在单纯颈动脉狭窄的患者中,虽然还未出现脑梗死的临床和影像学表现,但电生理已出现一定程度的异常,提示诱发电位(主要是SEP)可以作为颈动脉狭窄患者的早期的一个辅助检测方法。
Objective To investigate the value of evoked potential in the diagnosis of simple internal carotid artery stenosis. Methods Thirty patients with simple carotid artery stenosis who had been proved by carotid artery ultrasound and confirmed by brain CT or MRI to exclude cerebral infarction were selected and 30 healthy controls were selected as normal controls to make somatosensory evoked potential (SEP), brainstem auditory evoked Potential (BAEP) and brainstem visual evoked potential (VEP) detection. Results In patients with carotid artery stenosis, the abnormal rate of SEP was 40.0%, and the latency of each wave was longer than that of the control group. The amplitude of BAEP was significantly higher than that of the control group. The abnormal rate of BAEP was 6.67%, and the latency of each wave was no longer than that of the control group ; VEP anomalous rate of 3.33%, the latency of each wave compared with the control group no significant prolongation. Conclusions In patients with simple carotid artery stenosis, although no clinical and imaging findings of cerebral infarction have been found, there is some abnormality in electrophysiology, suggesting that the evoked potentials (mainly SEP) can be used as early stage of carotid stenosis A complementary testing method.