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本文报道42例急性心肌梗塞(AMI)患者血清线粒体天门冬氨酸转氨酶(m-AST)活力的动态变化。多数AMI患者血清m-AST活力在发病后12h明显升高,24h全部升高并达峰值。m-AST诊断AMI的敏感性为100%。特异性为93.5%,与CK-MB相似(P>0.20),可作为AMI诊断的酶学指标。本文未证实m-AST对AMI有预后评估价值。
This article reports the dynamic changes of mitochondrial aspartate aminotransferase (m-AST) activity in 42 patients with acute myocardial infarction (AMI). The serum m-AST activity of most patients with AMI was significantly increased at 12h after onset, all of them were increased and peaked at 24h. The sensitivity of m-AST diagnosis of AMI was 100%. The specificity was 93.5%, which was similar to CK-MB (P> 0.20) and could be used as an enzymatic index for the diagnosis of AMI. This article does not confirm that m-AST has prognostic value for AMI.