大多数学者认为大肠癌切除后的局部复发有三种原因:切除不完全,淋巴浸润,及种植转移。针对种植转移,作者于肠腔内应用甲醛灌注。已有证明,有生命力的癌细胞可以种植在肠道的断端,或由缝针带入肠壁内,或由肠液溢出带入腹腔内而引起腹膜或盆腔组织的复发。据动物实验研究,证明甲醛是一种杀伤癌细胞的药剂,容易得到,稳定性好。过去作者曾在膀胱癌切除前作膀胱内灌注,证明对预防手术后局部复发有效。自1968至1982年间,作者有40例用甲醛灌注,另145例未用任何药液灌注作为对照。游离肠袢前,在预计切断部位,各用两个钳子夹住一小段肠袢。靠近肿瘤的一端用碾压性钳子夹住,远离肿瘤的一端用非 Most scholars believe there are three causes of local recurrence after resection of colorectal cancer: incomplete resection, lymphatic infiltration, and implant metastasis. The authors used formaldehyde perfusion in the intestine for implantation. It has been demonstrated that viable cancer cells can be planted in the broken end of the intestine, or brought into the wall of the intestine by suture needles, or brought into the abdominal cavity by overflow of intestinal fluid to cause recurrence of peritoneal or pelvic tissue. According to animal experiments, it is proved that formaldehyde is an agent for killing cancer cells, which is easy to obtain and has good stability. In the past, the author had performed intravesical instillation before bladder cancer resection, which proved effective in preventing local recurrence after surgery. From 1968 to 1982, the authors infused 40 cases with formaldehyde, and the other 145 cases did not use any drug solution as a control. Prior to free intestinal fistula, a small section of intestinal fistula was clamped with two forceps at the site of the expected cut-off. The end near the tumor is clamped with roller compaction pliers.