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成都、兰州和长春生物制品研究所分别用上海丹麦2株卡介苗菌种在各所各生产3批卡介苗,并以上海所卡介苗为对照,同时分别在北京、杭州和广州3地区,对新生儿作接种后的异常反应和免疫效果比较。各地观察人数分别为9016、7240和9986人;阳转率分别为:成都苗95.6%~99.8%;兰州苗97.2%~98.9%;长春苗99.2%~100%;上海苗95.5%~99.1%;淋巴结总反应率为0.138%;分别为长春苗0.216%,成都苗0.241%,兰州苗0,上海苗0.075%。其中长春苗出现淋巴结化脓5例(0.059%),成都苗4例(0.085%)。广东省生物制品所也自制了丹麦2株卡介苗在广州地区作了观察,结果亦相近。
Chengdu, Lanzhou and Changchun Institute of Biological Products, respectively, two sets of Shanghai, Denmark, BCG strains in each of the three batches of BCG production, and the Shanghai-based BCG as a control, respectively, respectively, in Beijing, Hangzhou and Guangzhou 3 areas for newborns After the abnormal reaction and immune effect comparison. The numbers of observers in each area were 9016, 7240 and 9986, respectively; the positive conversion rates were 95.6% to 99.8% in Chengdu, 97.2% to 98.9% in Lanzhou, and 99.2% to 100% in Changchun %; Shanghai seedlings 95.5% ~ 99.1%; the total lymph node response rate was 0.138%; respectively 0.216% of Changchun seedlings, 0.241% of Chengdu seedlings, Lanzhou seedlings 0, 0.075% of Shanghai seedlings. Among them, 5 cases (0.059%) were found in Changchun seedling with suppurative lymph nodes and 4 cases (0.085%) in Chengdu seedling. Guangdong Institute of Biological Products also made two Danish BCG was observed in Guangzhou, the results are similar.