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目的 评价刺五加与弥可保联合应用对糖尿病周围神经病变的疗效。方法65例糖尿病周围神经病变患者随机分组对照观察,治疗组39例,给予刺五加 60ml,溶于NS 500ml,静脉点滴,每日一次,同时每日肌注弥可保500μg,共6周;对照组26例,单用弥可保肌注,每日500μg,共6周。结果治疗组痛觉过敏及感觉减退有效率达59%和67%,明显高于对照组的32%和39%,P<0.05;神经传导速度改善的有效率也有明显提高,P<0.05。结论刺五加与弥可保联合应用可明显改善对糖尿病周围神经病变的治疗效果。
Objective To evaluate the efficacy of acanthopanax senticosus combined with methycobal on diabetic peripheral neuropathy. Methods Sixty - five patients with diabetic peripheral neuropathy were randomly divided into control group (n = 39) and treatment group (n = 60). The treatment group was given Acanthopanax senticosus 60ml, dissolved in 500ml of NS, intravenously once a day, The control group, 26 cases, with Mi Kebao muscle injection alone, 500μg daily for 6 weeks. Results The effective rate of hyperalgesia and hypogonadism in the treatment group was 59% and 67%, which was significantly higher than that in the control group (32% and 39%, P <0.05). The effective rate of improving the nerve conduction velocity was also significantly improved (P <0. 05. Conclusion Acanthopanax senticosus combined with Mi Kebao can significantly improve the treatment of diabetic peripheral neuropathy.