硝普钠是一种混合配体的配合物,长期以来作为化学试剂使用;在医学上也有重要用途。它的降压性能1929年就有报导。它的降压强效、速效性能直到六十年代才逐渐引起人们的强烈兴趣和重视。临床上先后用于高血压和心血管病的治疗。特别是近十多年来研究认为:它是一种强力血管扩张剂,已被用来控制解剖动脉瘤、急性心肌梗塞等。但因它的水溶液对热和光均不稳定而易于失效,所以在医学上较多制成注射冻干粉针剂,急用时临时配制诸多不便。近三十年来很多作者对它的水溶液的稳定性相继作过研究,其中1966年G·E·Schumacher曾对硝普钠在某些介质中的稳定性通过观察比较方法提出了硝普钠水溶液的稳定体系,过滤灭菌避光保存,稳定2 Sodium nitroprusside is a mixed ligand complex that has long been used as a chemical reagent; it is also medically important. Its buck performance has been reported in 1929. Its antihypertensive efficacy, quick performance until the sixties gradually attracted the people’s intense interest and attention. Clinically for the treatment of hypertension and cardiovascular disease. In particular, over the past decade or so research that: it is a powerful vasodilator, has been used to control anatomical aneurysms, acute myocardial infarction. However, due to its aqueous solution of heat and light are unstable and prone to failure, so more in medicine made of injection freeze-dried powder injection, emergency preparation of a number of temporary inconvenience. In recent thirty years, many authors have studied the stability of its aqueous solution. In 1966, G. Schumacher once proposed the stability of sodium nitroprusside in some media by observing and comparing the aqueous solution of sodium nitroprusside Stable system, filtration and sterilization Save light, stable 2