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目的探讨分析在胃癌合并糖尿病患者术后使用全肠外营养(TPN)和早期肠内营养(EEN)的临床恢复效果。方法 86例胃癌合并糖尿病患者,根据术后采取的营养方式不同随机分为干预组和常规组,各43例。干预组使用EEN提供营养,常规组使用TPN提供营养。比较两组患者的营养指标恢复情况以及并发症发生情况等。结果干预组患者术后第8天的总胆红素(TBL)、谷草转氨酶(AST)、丙氨酸氨基转移酶(ALT)、总蛋白(TP)、血红蛋白(HGB)、体重(Wt)与常规组比较,差异无统计学意义(P>0.05);干预组患者术后第4天的TBL、AST、ALT、TP、HGB、Wt与常规组比较,差异有统计学意义(P<0.05)。干预组没有发生并发症的患者,常规组13例患者发生不良反应,干预组患者并发症发生率低于常规组(P<0.05)。结论在胃癌合并糖尿病患者术后营养中采用EEN的营养方式显示了较好的临床效果,且并发症的发生,在临床手术营养中应积极的使用EEN。
Objective To investigate the clinical effects of total parenteral nutrition (TPN) and early enteral nutrition (EEN) in patients with gastric cancer complicated with diabetes mellitus. Methods Totally 86 cases of gastric cancer with diabetes mellitus were randomly divided into intervention group and conventional group according to the different nutritional methods after operation. The intervention group used EEN to provide nutrition while the regular group used TPN to provide nutrition. Compare the recovery of nutritional indicators and the incidence of complications in two groups of patients. Results The levels of total bilirubin (TBL), aspartate aminotransferase (AST), alanine aminotransferase (ALT), total protein (TP), hemoglobin (HGB), body weight Compared with the conventional group, the difference was not statistically significant (P> 0.05). The difference of TBL, AST, ALT, TP, HGB and Wt in the intervention group was statistically significant (P <0.05) . In the intervention group, there were no complications, and 13 patients in the routine group had adverse reactions. The incidence of complications in the intervention group was lower than that in the conventional group (P <0.05). Conclusions The nutritional mode of using EEN in postoperative nutrition of patients with gastric cancer complicated with diabetes shows good clinical effect and the occurrence of complications. EEN should be actively used in clinical surgical nutrition.