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本文报告接锰工人外周血淋巴细胞的SCE频率与微核率都非常明显高于对照组(P〈0.001);对接锰组工人作SCE与微核的平行检测结果亦明显高于对照组。提示锰对细胞有致遗传学效应的作用;SCE与微核的检测可作为患者随访的指标,也可作为锰对机体早期损害的参考依据。
The SCE frequency and micronucleus rate of peripheral blood lymphocytes from manganese workers were significantly higher than those of the control group (P <0.001). The results of parallel detection of SCE and micronuclei in manganese workers were also significantly higher than that of the control group. Prompted manganese genetically-induced effect on cells; SCE and micronucleus test can be used as an indicator of patient follow-up, but also as a reference to the body of manganese damage early.