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癌症发病率随年龄的增长而上升,癌症已成为老年人的主要死因之一。老年癌症治疗中的一个重要方面是采取包括化疗在内的综合治疗。过去虽已明确化疗对常见的老年癌症如胃肠道癌、肺癌等均有缓解症状,延长生存期的治疗作用,但治疗方案大多是从姑息治疗的角度来考虑的。这一方面是由于老年生理功能的衰退,会使药物的吸收、代谢、分布和排泄有所改变,对药物的顺应性有所
The incidence of cancer increases with age, and cancer has become one of the major causes of death among the elderly. An important aspect of cancer treatment for the elderly is to take comprehensive treatment including chemotherapy. Although in the past, it has been clarified that chemotherapy can relieve the symptoms of common elderly cancers such as gastrointestinal cancer and lung cancer, prolonging the therapeutic effect of survival, but most of the treatment options are considered from the perspective of palliative care. This aspect is due to the decline of the physiological functions of the elderly, which will change the absorption, metabolism, distribution, and excretion of drugs, and the compliance with drugs has been improved.