目的探讨高频电凝在食管低级别上皮内瘤变治疗中的应用价值。方法采用胃镜下高频电凝治疗经病理诊断为食管低级别上皮内瘤变患者40例,分别于治疗后3、6、12个月行胃镜复查,观察病灶变化。结果所有病灶经高频电凝治疗后均无复发。结论高频电凝治疗食管低级别上皮内瘤变安全有效,简便易行,是食管癌高发区二级预防的有效手段。 Objective To investigate the value of high frequency electrocoagulation in the treatment of low esophageal intraepithelial neoplasia. Methods Forty patients with pathologically diagnosed low-grade intraepithelial neoplasia of esophagus underwent endoscopic high-frequency electrocoagulation were enrolled in this study. Gastroscopy was performed at 3, 6, and 12 months after treatment, and the changes of lesions were observed. Results All lesions had no recurrence after high frequency electrocoagulation. Conclusions High-frequency electrocoagulation is safe and effective in treating esophageal low-grade intraepithelial neoplasia and is simple and effective. It is an effective measure to prevent secondary esophageal cancer in high incidence area.