论文部分内容阅读
先前研究已证实，肝脏、心脏和小肠等器官移植排斥仅应时的大鼠血浆中ＮＯ２－明显升高，本研究旨在运用大鼠原位肾移植模型，采用示波极谱法动态测定肾移植术后大鼠血浆中ＮＯ２－的含量，从而说明ＮＯ２－在肾移植排斥反应中的作用。结果显示，大鼠异糸肾移植术后４天起，各组移植肾均出现明显的排斥反应的病理改变，而异系肾移植术后２ｄ起，大鼠血浆中ＮＯ２－的含量较对照组明显升高（Ｐ＜０．０５）。说明了大鼠肾移植排斥仅应时，血浆中ＮＯ２－水平升高，且提示血浆中ＮＯ２－的升高可以预示肾移植排斥反应的发生
Previous studies have confirmed that liver, heart and small intestine and other organ transplant rejection only rat plasma NO2- significantly increased, the purpose of this study is to use rat orthotopic kidney transplantation model, the use of oscillopolarographic dynamic determination of renal The content of NO2- in plasma of rats after transplantation shows the role of NO2- in renal allograft rejection. The results showed that there were obvious pathological changes of allograft rejection in all groups after 4 days from transplantation of heterophylla in rats. Compared with the control group, the content of NO2- Was significantly higher (P <0.05). It shows that the rejection of renal allograft in rats should only be increased when the level of NO2- in plasma increases, and the increase of NO2- in plasma can predict the occurrence of renal allograft rejection