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EB(Epstein Barr)病毒是一种疱疹型DNA病毒,在电子显微镜下其直径为100～150nm,至少由33种不同的多肽组成。EB病毒感染在儿科较为常见,感染后可有多种表现形式,如:无临床症状的原发感染、传染性单核细胞增多症、慢性感染、恶性淋巴增殖综合征及低丙种球蛋白血症等。近年来通过临床和实验室研究,使本病在流行病学、临床诊断和实验室检查等方面有了较大的进展,本文就有关问题综述如下: 血清流行病学 EB病毒感染无明显季节性和性别差异,但与社会经济地位及卫生条件明显相关。例如在发展中国家,3岁儿童的血清阳性率为80～90％,而西德5岁儿童仅为
The Epstein Barr virus is a herpesvirus that has a diameter of 100-150 nm under electron microscopy and consists of at least 33 different polypeptides. Epstein-Barr virus infection is more common in pediatrics and can manifest itself in multiple forms after infection, such as primary clinical infection, infectious mononucleosis, chronic infection, malignant lymphoproliferative syndrome, and hypogammaglobulinemia Wait. In recent years through clinical and laboratory studies, the disease in the epidemiology, clinical diagnosis and laboratory tests have made great progress, the paper summarizes the relevant issues are as follows: Serological Epidemiology EB virus infection no significant seasonal And gender differences, but clearly related to socio-economic status and health conditions. In developing countries, for example, the seroprevalence of 3-year-olds is 80-90%, while the 5-year-old children of West Germany are only