小儿肺炎是儿内科多发病及常见病,常常严重威胁小儿健康甚至生命。小儿肺炎中细菌性约占62%左右〔1〕,临床治疗多使用单一抗生素,严重者可两种抗生素联合使用,临床配伍方式多以经验用药及依据痰液细菌培养及药物敏感实验灵活选用,但大环内酯类(如红霉素,阿奇霉素等)与β-内酰胺 Pediatric pneumonia is a frequent internal medicine and common disease, often serious threat to pediatric health and even life. Bacterial pneumonia in children accounts for about 62% 〔1〕, the clinical treatment of more than a single antibiotic, severe cases can be combined with two antibiotics, clinical compatibility and more based on empirical medication and based on sputum bacterial culture and drug-sensitive experiments flexible selection, However, macrolides (such as erythromycin, azithromycin, etc.) and β-lactam