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目的观察局部晚期宫颈癌新辅助化疗的疗效及应用价值。方法宫颈癌22例中Ⅰb期(巨块型直径≥4cm)10例,Ⅱa期6例,Ⅱb期6例,均采用VBP方案化疗,根据近期疗效予以进一步手术或放疗。结果近期有效率90.9%(20/22),其中Ⅰb期1例,Ⅱa期1例,经两周期化疗后属病理完全缓解,完全缓解率9%,化疗结束后手术切除率90.9%。结论宫颈癌术前化疗使癌灶缩小,提高了手术切除率及患者的生存质量。
Objective To observe the efficacy and value of neoadjuvant chemotherapy for locally advanced cervical cancer. Methods Twenty-two cases of cervical cancer were treated with VBP chemotherapy in 10 cases of stage Ⅰb (bulky type ≥ 4cm in diameter), 6 cases of stage Ⅱ a and 6 cases of stage Ⅱb, and further surgery or radiotherapy was performed according to the short-term curative effect. The results of the recent efficiency of 90.9% (20/22), of which Ⅰ b in 1 case, Ⅱ a period of 1 case, after two cycles of chemotherapy is a complete remission, the complete remission rate was 9%, after the end of chemotherapy, the surgical resection rate was 90.9%. Conclusion Preoperative chemotherapy of cervical cancer reduces the tumor size and improves the surgical resection rate and quality of life of the patients.