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为探讨卵浆内单精子显微注射(ICSI)及经皮穿刺附睾吸取精子(PESA)治疗严重少、弱、畸形精子及精道不通男性不育患者的价值,对7对男性不育夫妇采用ICSI或PESA+ICSI治疗。对女方常规促超排卵、取卵,共获卵子97个,其中成熟卵子81个,行ICSI后存活72个,受精率为62.5％,每周期可移植胚胎2～4个,临床妊娠6例。于1998年2月16日足月出生一正常男婴(PESA+ICSI)。初步研究表明:ICSI或PESA+ICSI技术是治疗男性因素不育的有效方法,尤其PESA+ICSI技术为男性输精管绝育(结扎、粘堵)受术者提供生殖保险。
In order to explore the value of intracytoplasmic sperm injection (ICSI) and percutaneous aspiration of epididymal sperm (PESA) in the treatment of patients with severe, weak, abnormal sperm and fine labyrinth infertility, seven male infertile couples were used ICSI or PESA + ICSI treatment. The women routinely induced superovulation and ovulation, and a total of 97 eggs were obtained, of which 81 were mature, 72 survived after ICSI, fertilization rate was 62.5%, 2 ~ 4 embryos were transplanted per cycle and 6 cases were clinical pregnancy. A normal baby boy (PESA + ICSI) was born during February 16, 1998. Preliminary studies have shown that: ICSI or PESA + ICSI technology is an effective way to treat male infertility. In particular, PESA + ICSI provides reproductive insurance for men underwent vasectomy (ligation and sticking).