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自从δ因子在南意大利被偶然发现,并于1977年首次报道后,Rizzetto等人对此进行了更深入的研究,已有充分的证据说明δ因子是一种新的致肝炎病毒。Rizzetto等建议将δ因子称为D型(或丁型)肝炎病毒(HDV),所致的疾病称为D型病毒性肝炎(HD)。HDV所致的病毒性肝炎,可能久已存在,只是最近才被发现。Ponzetto等对美国4个厂家在1962年～1977年间用1944年～1977年收集的血浆制备的血清免疫球蛋白(ISG)进行了
Since the δ-factor was discovered by chance in southern Italy and was first reported in 1977, Rizzetto et al. Conducted a more in-depth study and there is sufficient evidence that the delta-factor is a novel hepatitis virus. Rizzetto et al. Suggest that the delta factor is referred to as type D (or type D) hepatitis virus (HDV) and the disease caused is called type D viral hepatitis (HD). The viral hepatitis caused by HDV may have existed for a long time and has only recently been found. Ponzetto and other US manufacturers in the 1962 to 1977 with the collection of 1944 to 1977 plasma prepared serum immunoglobulin (ISG) were