妇女梅毒和艾滋病病毒(HIV)感染,在妊娠期均可通过母婴传播造成不良的妊娠结局。梅毒与HIV感染均为性传播疾病,具有相同的流行危险因素,感染者具有相似的高危行为,常表现出较高的联合感染率。该文综述了梅毒对HIV感染的易感性、临床表现、筛查、流行特征、母婴传播等方面影响的研究进展,为开展孕产期联合预防HIV感染和梅毒传播综合服务提供参考。 Women with syphilis and HIV infection may have adverse pregnancy outcomes through mother-to-child transmission during pregnancy. Syphilis and HIV infections are all sexually transmitted diseases with the same epidemic risk factors. The infected persons have similar high-risk behaviors and often show a high co-infection rate. This review summarizes the research progress of syphilis on the susceptibility to HIV infection, clinical manifestations, screening, epidemiological characteristics, mother-to-child transmission and other aspects of syphilis, and provides references for the joint prevention of HIV infection and syphilis transmission during pregnancy and childbirth.