论文部分内容阅读
目的：观察评价增压舱在高海拔地区对人体夜间睡眠过程中血氧饱和度和通气功能的影响。方法8名从低海拔地区来到高海拔地区1年的男性汉族志愿者，年龄（19.3±2.1）岁，于海拔4532 m处进行两次夜间睡眠监测的自身对照观察。第一天睡眠时不给予任何干预（对照组），第二天睡在增压舱中，给予增压0.2ATA（实验组）。分别记录脉搏血氧饱和度（SpO2）、呼吸暂停低通气指数（AHI）、氧减指数（DI）和周期性呼吸（PB）。结果实验组睡前SpO2、夜间平均SpO2、和最低SpO2分别为（94.13±0.83）%、（91.63±0.92）%，和（85.63±1.30）%，均显著高于对照组[（84.25±1.04）%、（81.38±1.41）%和（74.13±1.46）%，均P＜0.01]。实验组的AHI为（4.63±3.11）/h，显著低于对照组（9.50±5.18）/h（P＜0.05）；实验组的DI为（4.50±3.42）/h，显著低于对照组[（15.63±6.97）/h，P＜0.01）。实验组的PB为（6.13±6.36）min，显著低于对照组[（17.25±6.67）min，P＜0.01]。结论增压舱在高海拔环境下能明显提高人体夜间氧合，改善睡眠质量。“,”Objective To investigate the effects of hyperbaric cabin on arterial oxygen saturation and ventilation during sleep at high altitude. Methods Eight healthy volunteers, all of Han nationality, aged (19.3 ± 2.1), all males, who migrated from low altitude areas to high altitude area 1 year before, stayed in the experimental zone at the altitude of 4 532 m for 2 days. In the first night they slept without the hyperbaric cabin (as control group), and in the second night they slept in the hypobaric cabin with the air pressure of 0.2 absolute atmospheric pressure (ATA) higher (as experiment group). Polysomnography (PSG) was conducted to record the pulse oxygen saturation (SpO2), apnea hypopnea index (AHI), desaturation index (DI), and periodic breathing (PB). Results The SpO2 before sleeping of the experiment group was (94.13±0.83)%, significantly higher than that of the control group [(84.25±1.04)%, P<0.01], the mean SpO2 during sleeping of the experiment group was (91.63 ± 0.92)%, significantly higher than that of the control group [( 81.38 ± 1.41)%, P<0.01], the lowest SpO2 of the experiment group was (85.63 ± 1.30)%,significantly higher than that of the control group [(74.13±1.46)%, P<0.01], the AHI of the experiment group was 4.63±3.11/h, significantly lower than that of the control group (9.50 ± 5.18/h., P<0.01), the DI of the experiment group was 4.50 ± 3.42/h, significantly lower than that of the control group (15.63 ± 6.97/h, P<0.01), and the PB of the experiment group was (6.13 ± 6.36) min, significantly shorter than that of the control group [(17.25 ± 6.67) min, P<0.01). Conclusion Hyperbaric cabin raises the oxygenation during sleep, thus improving the sleep quality.