论文部分内容阅读
目的了解邛崃市医疗中心医院临床分离病原菌的种类及对常用药物的耐药性，为临床抗菌药物的使用提供参考。方法对医院2012年住院部分离菌株的种类及其药敏采用WHONET5.4软件进行数据分析。结果2012年共收集到2494株非重复临床分离株，革兰氏阴性菌1504株，占60.30%；革兰氏阳性菌917株，占36.77%，真菌73株，占2.92%。检出产ESBLs大肠埃希菌、肺炎克雷伯菌分别为56.32%、14.35%，产ESBLs肺炎克雷伯菌远低于国内多数文献报道（＞50%）。检出的237株金黄色葡萄球菌中耐甲氧西林金黄色葡萄球菌24例，检出率为10.13%，远低于国内某些文献报道（＞50%）。261株表皮葡萄球菌中检出耐甲氧西林表皮葡萄球菌187例，检出率为71.54%。结论由于各种细菌耐药情况差别较大，建议临床积极开展细菌培养，以药敏试验结果为依据，有针对性用药，以控制和减缓细菌耐药性的增长，控制医院感染。“,” OBJECTIVE To investigate the species and the drug resistance to common antibacterials of the pathogenic bacteria isolated from patients of Qionglai Medical Center Hospital, so as to provide reference for the clinical selection of antibiotics. METHODS The species of the kinds of microorganisms isolated during year 2012 and their antibacterial-resistance were analyzed by software WHONET5.4. RESULTS A total of 2494 clinical isolates of non-repeated bacteria were isolated, including 1504(60.3%) strains of gram-negative bacteria , 917(36.77%) strains of gram-positive bacteria, and 73(2.92%) strains of fungi. The positive rates of ESBLs-producing Esche-richia coli and Klebsiel a were 56.32%、14.35%. The positive rates of ESBLs-producing Klebsiel a was lower than reported in china(>50%). Rate of Methicil in-resistant Staphylococcus aureus(MRSA) was 24(10.13%)strains, lower than reported in china(>50%). Rate of Methicil in-resistant S. epidermidisaureus was 87(71.54%)strains. CONCLUTION Due to the large variety of bacterial resistance varies, so it is necessary to strengthen bacterial culture. reasonably select the antibiotics based on the drug susceptibility testing, so as to control or slow the growth of bacterial resistance and hospital infections .