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目的观察安儿宁颗粒治疗小儿咳嗽痰热型的临床疗效。方法 180例小儿咳嗽痰热型患儿随机分为对照组和治疗组,各90例。对照组予小儿感冒颗粒口服,治疗组予安儿宁颗粒口服,2组均以3 d为1个疗程,连续治疗2个疗程后观察临床疗效。结果对照组总有效率为75.56%,治疗组为93.33%,2组比较,差异有统计学意义(P<0.05);治疗前2组中医证候评分比较,差异无统计学意义(P>0.05),具有可比性;治疗后2组各项中医证候评分较同组治疗前均显著改善,且治疗组改善程度优于对照组(P<0.05);治疗组咳嗽消失时间、热退时间、痰鸣音消失时间均明显短于对照组,经统计学分析,差异有统计学意义(P<0.05);治疗前2组WBC,C-反应蛋白(CRP)水平经统计学分析,差异无统计学意义(P>0.05);治疗后2组WBC,CRP水平较治疗前均明显降低,且治疗组降低更显著(P<0.05)。结论安儿宁颗粒治疗小儿咳嗽痰热型临床疗效明显优于小儿感冒颗粒,可在短时间内有效改善患儿的临床症状,促进WBC及CRP水平的恢复,值得在临床上推广应用。
Objective To observe the clinical efficacy of Anleining Granule in treating children with cough and phlegm type. Methods 180 children with cough phlegm type were randomly divided into control group and treatment group, 90 cases each. The control group was given orally with cold granules for children. The treatment group was orally administered with Anlening Granules. Both groups were treated with 3 days for 1 course of treatment. After 2 courses of continuous treatment, the clinical effect was observed. Results The total effective rate was 75.56% in the control group and 93.33% in the treatment group. There was significant difference between the two groups (P <0.05). There was no significant difference in the TCM syndrome scores between the two groups before treatment (P> 0.05 ), Comparable; after treatment, the scores of TCM syndromes in both groups were significantly improved compared with those in the same group before treatment, and the improvement in the treatment group was better than that in the control group (P <0.05); the cough disappearing time, The disappearance time of phlegm and phlegm was significantly shorter than that of the control group, and the difference was statistically significant (P <0.05). The levels of WBC and C-reactive protein (CRP) in the two groups before treatment were statistically different (P> 0.05). The levels of WBC and CRP in the two groups after treatment were significantly lower than those before treatment, and the treatment group decreased more significantly (P <0.05). Conclusion Anlein Granules treatment of children with cough and phlegm type clinical efficacy was significantly better than children with cold particles, can effectively improve the clinical symptoms in children in a short time and promote the recovery of WBC and CRP levels, it is worth popularizing the clinical application.