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可溶性白细胞分化抗原40配体作为急性冠脉综合征时血小板活化的指标,较肌钙蛋白而言,能提供动脉粥样斑块破裂和血小板激活的更为直接的信息。具有重要的早期诊断和预测意义。大量的研究已经证实了可溶性白细胞分化抗原40配体与急性冠脉综合征的密切关系。因此,临床上,将可溶性白细胞分化抗原40配体用于对急性冠脉综合征预后的预测与评估具有重要意义。本综述阐述可溶性白细胞分化抗原40配体的来源,可溶性白细胞分化抗原40配体与急性冠脉综合征关系,以及可溶性白细胞分化抗原40配体对急性冠脉综合征预后的预测价值。
Soluble leukocyte differentiation antigen 40 ligand, as an indicator of platelet activation during acute coronary syndrome, provides more direct information than troponin on atherosclerotic plaque rupture and platelet activation. It has important significance for early diagnosis and prediction. A large number of studies have confirmed the close relationship between soluble leukocyte differentiation antigen 40 ligand and acute coronary syndrome. Therefore, clinically, soluble leukocyte differentiation antigen 40 ligand for the prognosis of acute coronary syndrome prognosis and evaluation of great significance. This review presents the sources of soluble leukocyte differentiation antigen 40 ligand, the relationship between soluble leukocyte differentiation antigen 40 ligand and acute coronary syndrome, and the predictive value of soluble leukocyte differentiation antigen 40 ligand for prognosis of acute coronary syndrome.