卡马西平系一线抗惊厥药,它也可用于治疗急性精神分裂症与狂躁症。卡马西平致精神病较为罕见,本文报道一例顽固性癫痫患者,长期用丙戊酸钠治疗,在加用固定的卡马西平方案后不久便出现急性精神病。患者为一23岁男性,患癫痫已接受丙戊酸钠治疗7年。但该患者无精神病史,智力较正常低,EEG示右颞后区有活动性δ波,脑CT正常。入院时,患者 Carbamazepine is a first-line anticonvulsant that can also be used to treat acute schizophrenia and mania. Carbamazepine is a rare form of psychosis. This article reports a patient with refractory epilepsy who was treated with sodium valproate for long periods of time and developed acute psychosis soon after adding a fixed carbamazepine regimen. The patient was a 23-year-old man with epilepsy who had been treated with sodium valproate for 7 years. However, the patient had no mental illness and had lower intelligence than normal. EEG showed active delta wave in the right temporal region and normal brain CT. On admission, the patient