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作者等对放置含雌二醇77mg和D-18甲基炔诺酮96-150mg的聚硅氧烷阴道环(CVR)的39名妇女进行了研究。CVR外径为61mm,厚度为9.5mm,甾体被浸于薄层聚硅氧烷中间层中。于周期第5天将环置入阴道中,3周后取出一周,以允许撤退性出血,此后一直按三周置环,一周取出的方案反复使用。研究分二阶段进行,首先研究了8名有生育力但经绝育手术的健康妇女(Ⅰ组),她们的年龄为22—35岁,有规则月经史,有排卵的间接证明(置CVR前一周
The authors studied 39 women placed polysiloxane vaginal ring (CVR) containing 77 mg of estradiol and 96-150 mg of D-18 norgestrel. The CVR has an outer diameter of 61 mm and a thickness of 9.5 mm. The steroid is immersed in a thin layer of polysiloxane interlayer. The ring will be placed on the 5th day of the cycle in the vagina, 3 weeks after the withdrawal of a week to allow evacuation of bleeding, has been ring set three weeks later, a week out of the program repeatedly used. The study was conducted in two phases. First, eight healthy women (Group Ⅰ) with fertility but undergoing sterilization were studied. Their age ranged from 22 to 35 years. They had regular menstruation with indirect evidence of ovulation (the last week of CVR