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目的:探讨多发性硬化(MS)与视神经脊髓炎(NMO)首发表现的临床差异。方法:将本院2014年1月至2016年1月收治的MS患者80例以及NMO患者76例作为本研究对象。针对两组患者的发病形式、首发表现以及影像学检测结果等实施临床对比。结果:在NMO组患者中,视力下降不大于0.1的患者26例,MS组患者为2例;两组患者差异具有统计学意义(P<0.05)。对于MS患者,其脊髓病灶形态主要呈现为卵圆形,周边体现为不对称的现象,对于NMO患者,大多体现为纵向融合以及居中病灶。在首发症状表现方面,NMO组患者与MS组患者有所不同。NMO组患者主要表现为视力下降,MS组主要表现为肢体麻木以及力弱,两组比较,差异具有统计学意义(P<0.05)。结论:NMO患者与MS患者在疾病实体表现方面有所不同,两类疾病患者在易感性、首发表现以及影像表现等方面,均呈现出的一定的差异。
Objective: To investigate the clinical manifestations of multiple sclerosis (MS) and optic neuromyelitis (NMO). Methods: 80 patients with MS and 76 NMO patients admitted to our hospital from January 2014 to January 2016 were selected as the study subjects. The two groups of patients for the incidence of the disease, the first performance and imaging test results such as the implementation of clinical comparison. Results: In the NMO group, there were 26 cases of vision loss less than 0.1 and 2 cases of MS group. The difference between the two groups was statistically significant (P <0.05). For patients with MS, the morphology of the spinal cord lesions mainly presented as oval, around the body as an asymmetry phenomenon, for NMO patients, mostly manifested as longitudinal fusion and the central lesion. In terms of first symptom manifestations, patients in the NMO group were different from patients in the MS group. Visual acuity decreased mainly in NMO group. The main manifestations of numbness and weakness in MS group were statistically significant (P <0.05). CONCLUSIONS: NMO patients and MS patients differ in the manifestation of disease entities. Both patients show some differences in their susceptibility, initial performance and imaging performance.