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目的探讨ＡｇＮＯＲ和肥大细胞与大肠癌诊断及分级的关系。方法对４４例大肠癌，１２例大肠腺瘤，１６例癌旁粘膜做ＡｇＮＯＲ计数及肥大细胞计数。结果ＡｇＮＯＲ和肥大细胞计数在大肠腺瘤及腺癌间差异有显著性（Ｐ＜０．０１），ＡｇＮＯＲ计数随大肠腺癌分化程度的降低而增多，两者呈负相关。肥大细胞计数随大肠癌分化程度的降低而降低，两者呈正相关。结论ＡｇＮＯＲ和肥大细胞计数对大肠癌诊断、分级及预后有重要参考价值
Objective To investigate the relationship between AgNOR and the diagnosis and grading of mast cells and colorectal cancer. Methods AgNOR counts and mast cell counts were performed in 44 cases of colorectal cancer, 12 cases of colorectal adenomas, and 16 cases of paraneoplastic mucosa. Results AgNOR and mast cell counts were significantly different between colorectal adenomas and adenocarcinomas (P<0.01). AgNOR counts increased with the degree of differentiation of colorectal adenocarcinomas. There was a negative correlation between them. Mast cell counts decreased with the degree of differentiation of colorectal cancer, a positive correlation between the two. Conclusion AgNOR and mast cell count have important reference value for the diagnosis, classification and prognosis of colorectal cancer