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目的探讨血清镁水平与ICU重症患者预后的关系。方法 322例ICU重症患者根据不同血清镁水平分为低血镁组87例(A组,血清镁<0.7mmol/L)、正常血镁组213例(B组,血清镁0.7~1.2mmol/L)和高血镁组22例(C组,血清镁>1.2mmol/L)。记录患者疾病组成、实验室指标、机械通气时间、ICU住院时间等,采用急性生理学与慢性健康状况评分系统Ⅱ(APACHEⅡ)评分和序贯器官衰竭(SOFA)评分评估患者病情,分析ICU重症患者死亡的危险因素。结果 A组原发疾病为胸腹部术后和脓毒血症的患者比例高于B组、C组(P<0.01)。A组APACHEⅡ评分、SOFA评分、机械通气时间、ICU住院时间、病死率均高于B组(P<0.05)。APACHEⅡ评分、SOFA评分、血清镁水平均为影响ICU重症患者死亡的独立危险因素(P<0.05)。结论血清镁水平与ICU重症患者病死率密切相关,需重视ICU重症患者低镁血症的发生。
Objective To investigate the relationship between serum magnesium level and the prognosis of severe ICU patients. Methods A total of 322 ICU critically ill patients were divided into two groups based on different levels of serum magnesium: 87 in the low magnesium group (group A, serum magnesium <0.7 mmol / L) and 213 in the normal magnesium group (group B, serum magnesium 0.7-1.2 mmol / L ) And hypermagnesemia group (n = 22) (group C, serum magnesium> 1.2 mmol / L). The patient’s disease composition, laboratory parameters, mechanical ventilation time, ICU length of stay and so on were recorded. APACHEⅡscore and SOFA score were used to evaluate the patient’s condition, and the death of ICU critically ill patients was analyzed Risk factors. Results The proportion of patients with primary disease in group A after thoracoabdominal surgery and sepsis was higher than those in group B and C (P <0.01). A group APACHE Ⅱ score, SOFA score, mechanical ventilation time, ICU hospital stay, mortality were higher than the B group (P <0.05). APACHE Ⅱ score, SOFA score and serum magnesium level were independent risk factors for the death of ICU critically ill patients (P <0.05). Conclusions Serum magnesium level is closely related to the mortality of ICU critically ill patients. It is necessary to pay attention to the occurrence of hypomagnesemia in severe ICU patients.