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目的:探讨不同肝功能状况肝硬变电解质紊乱特点。方法:对154例肝硬变患者进行Child-Pugh肝功能分级,血K~+、Na~+、Cl~-、Ca~(2+)检测由自动生化分析仪完成。结果:4种离子紊乱依次是:低Na~+>低C国~->低Ca~(2+)>低K~+;Child-Pugh肝功能分级与电解质紊乱有关:4种离子均数与A、B、C分级有关,其中Na~+、Cl~-变化具统计学意义(P<0.01),4种离子紊乱百分率、电解质紊乱病例数与A、B、C分级具显著性差异(P<0.05,P<0.01);离子紊乱模式以低Na~+最多见,部分低Na~+、低Cl~-呈直线相关。结论:肝硬变患者电解质紊乱随肝功能的Child-Pugh分级的增高而明显。
Objective: To investigate the different characteristics of liver cirrhosis electrolyte imbalance. Methods: Child-Pugh liver function was graded in 154 patients with cirrhosis. The blood K +, Na +, Cl ~ - and Ca 2+ were detected by automatic biochemical analyzer. Results: The order of the four ion disorders was: low Na ~ +> low C ~ ~> low Ca ~ (2 +)> low K ~ +; Child-Pugh liver function classification was related to electrolyte disturbance: (P <0.01). The percentage of four ion disorders and the number of electrolytes disorders were significantly different from those of A, B and C (P <0.05, P <0.01). The mode of ion disturbance was linearly correlated with the low Na ~ +, the low Na ~ + and the low Cl ~. Conclusion: Electrolyte disorder in cirrhotic patients is markedly elevated with Child-Pugh classification of liver function.