Fishing activities can alter the structure of marine food webs by the selective removal of some species. The changes in the marine food webs of the Hormuzgan waters of the Persian Gulf, Iran were assessed, based on estimates of the mean trophic index(MTI) and Fishing in Balance index(FiB), and on landing profile of the exploited marine community(49 species) during the period, 2002–2011. The total landings( Y_t)( R =0.88, P <0.001) increased gradually while the Y_t of carnivores has slightly declined, and the Y_t of herbivores, detritivores and omnivores has increased. Consequently, the MTI significantly decreased( R =-0.69, P <0.05) at a rate of 0.11 during this decade. The MTI showed a decreasing trend, which indicates exploitation of marine resources. The Fi B index also showed a downward trend and negative values from 2002 to 2009, which may be associated with unbalanced structure in the fisheries, but an upward trend from 2009 to 2011. The time variation of the landing profile showed two periods with significant differences in their species composition( R =0.88; P =0.005), and based on analysis of similarity, species have been identified as discriminator species, namely Thunnus albacores and Benthosema pterotum. Results indicate that changes in MTI reflected changes in the Hormuzgan landing structure. The examination of the MTI, FBI, and landing profile(LP) temporal pattern suggests that the status of fishery resources in Hormuzgan inshore waters is overexploited, and provides evidence of the probability that a fishing down process is occurring in this area, and that this trend may continue in the long-term. Therefore, environmental fisheries management and conservation programs should be prioritized for these valuable resources. The changes in the marine food webs of the Hormuzgan waters of the Persian Gulf, Iran were assessed, based on estimates of the mean trophic index (MTI) and Fishing in Balance index (FiB), and on landing profile of the exploited marine community (49 species) during the period, 2002-2011. The total landings (Y_t) (R = 0.88, P <0.001) The MTI showed a decreasing trend, which had a decline of 0.11 during this decade. The MTI showed a declining trend (r = -0.69, P <0.05), and the Y_t of herbivores, detritivores and omnivores had increased. The exploitation of marine resources. The Fi B index also showed a downward trend and negative values ​​from 2002 to 2009, which may be associated with unbalanced structure in the fisheries, but an upward trend from 2009 to 2011. The time variation of the landing profile sh owed two periods with significant differences in their species composition (R = 0.88; P = 0.005), and based on analysis of similarity, species have been identified as discriminator species, namely Thunnus albacores and Benthosema pterotum. Results indicate that those changes in MTI reflected changes in the Hormuzgan landing structure. The examination of the MTI, FBI, and landing profile (LP) temporal pattern suggests that the status of fishery resources in Hormuzgan inshore waters is overexploited, and may evidence that the probability that a fishing down process is occurring in this area, and that this trend may may in the long-term. therefore, environmental fisheries management and conservation programs should be prioritized for these valuable resources.