衣原体是引起多种人类疾病的专性胞内寄生的革兰阴性菌。接种疫苗是预防和控制衣原体感染的经济有效的途径。目前,衣原体疫苗的研究主要集中在亚单位疫苗、载体疫苗、DNA疫苗等,这些疫苗往往需要免疫佐剂来增强其免疫效果。现就佐剂在衣原体疫苗中应用的研究进展作一综述。 Chlamydia is the obligate intracellular parasitic gram-negative bacterium that causes many human diseases. Vaccination is a cost-effective way to prevent and control chlamydial infections. At present, chlamydial vaccines mainly focus on subunit vaccines, vector vaccines, DNA vaccines, etc. These vaccines often require immune adjuvants to enhance their immune effect. Now the application of adjuvants in Chlamydia vaccine research progress are reviewed.