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目的:了解补肾祛湿中药联合多沙唑嗪治疗慢性附睾炎的临床疗效。方法:64例慢性附睾炎患者随机均分为2组,每组32例。对照组仅服用多沙唑嗪,治疗组采用补肾祛湿中药联合多沙唑嗪治疗,每组患者接受药物治疗4周。使用慢性附睾炎症状指数评分表(CESI)、焦虑自评量表(SDS)、抑郁自评量表(SAS)等对治疗前后临床症状进行评估,并评价其疗效。结果:两组经治疗后,在CESI总均分、疼痛评分以及生活质量评分上皆有显著性改善(P<0.05);治疗组与对照组相比疗效更佳,差异有显著性(P<0.05)。治疗后两组患者在SAS及SDS评分上皆有显著性降低(P<0.05),但两组间比较无显著性差异(P>0.05)。结论:单独使用多沙唑嗪及补肾祛湿中药联合多沙唑嗪对慢性附睾炎皆有明显的临床疗效,但联合用药是一种更佳的治疗方法。
Objective: To understand the clinical efficacy of Bushen Qushi Chinese medicine combined with doxazosin in the treatment of chronic epididymitis. Methods: Sixty-four patients with chronic epididymitis were randomly divided into two groups (n = 32 in each group). The control group only took doxazosin, the treatment group was treated with Bushen Qushi Chinese medicine plus doxazosin, and each group received medication for 4 weeks. The clinical symptoms before and after treatment were evaluated by CESI, SAS and SAS, and the curative effect was evaluated. Results: After treatment, the two groups had significant improvement in the total score of CESI, pain score and quality of life score (P <0.05), and the curative effect in the treatment group was better than that in the control group (P < 0.05). After treatment, the scores of SAS and SDS in both groups were significantly decreased (P <0.05), but there was no significant difference between the two groups (P> 0.05). Conclusion: Doxazosin alone and Bushen Qushi Chinese medicine combined with doxazosin have significant clinical effects on chronic epididymitis, but combination therapy is a better treatment.