目的对耳鼻喉头颈外科患者医院感染进行目标性监测与分析,为临床预防感染提供依据。方法选取医院2012年2月-2013年12月收治的326例耳鼻咽喉头颈外科患者作为研究对象,采用目标性监测方法对患者的感染情况进行记录和分析,根据监测结果针对相关危险因素制定目标性干预措施,并选取2014年3-11月收治的158例患者作为研究对象,其中给予常规治疗的79例患者为对照组,另给予目标性干预措施的79例患者为干预组,对比两组患者治疗过程中医院感染情况,并对结果进行比较分析。结果 326例耳鼻咽喉头颈外科患者中发生医院感染49例,发生率为15.03%,其中以呼吸系统感染为主,占67.34%,其次为泌尿系统、循环系统和手术切口感染;共检出病原菌56株,其中革兰阴性菌39株占69.64%,革兰阳性菌9株占16.07%,真菌8株占14.29%;其中呼吸机使用、中心静脉导管置管以及留置导尿管3种侵入性操作的感染率分别为25.96%、5.95%和3.53%;干预组感染患者住院天数以及住院费用均较对照组明显减少,差异有统计学意义(P<0.05)。结论目标性监测能有效发现医院感染的影响因素,目标性干预措施则可有效地降低患者的医院感染率、住院天数以及治疗费用,对于改善医疗质量有着积极的作用。 Objective To monitor and analyze the nosocomial infection of patients with otolaryngological head and neck surgery to provide evidence for clinical prevention of infection. Methods A total of 326 cases of otolaryngology head and neck surgical patients admitted from February 2012 to December 2013 in our hospital were selected as research subjects. The patients’ infection status was recorded and analyzed by targeted monitoring method. Targets were set according to the monitoring results for the relevant risk factors Interventions and selected 158 patients admitted from March to November 2014 as the object of study, of which 79 patients given conventional treatment as control group, and the other 79 patients given targeted intervention intervention group, compared with two groups of patients Hospital infection during treatment, and comparative analysis of the results. Results Of the 326 patients with otorhinolaryngology head and neck surgery, 49 cases of nosocomial infection occurred in the patients, accounting for 15.03%, of which respiratory system was predominant, accounting for 67.34%, followed by urinary system, circulatory system and surgical incision infection. Pathogenic bacteria 56 Among them, 39 strains of Gram-negative bacteria accounted for 69.64%, 9 strains of Gram-positive bacteria accounted for 16.07% and 8 strains of fungi accounted for 14.29%. Among them, 3 invasive procedures including ventilator, central venous catheter and indwelling catheter Were 25.96%, 5.95% and 3.53%, respectively. The hospitalization days and the cost of hospitalization in the intervention group were significantly lower than those in the control group (P <0.05). Conclusions Targeted monitoring can effectively find the influencing factors of nosocomial infection. Targeted interventions can effectively reduce nosocomial infection rate, hospitalization days and treatment costs, which has a positive effect on improving the quality of medical care.