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在制备中草药注射剂的过程中,溶媒回收也是工艺上的一个重要环节。本文介绍一套实验室装置,可供医院制剂室应用,也可供工厂产品试制研究以及院校药化教学时参考。一、结构见附图。二、操作开启真空泵16,打开止水夹6,经进液管7吸入待回收溶媒的药液至蒸馏烧瓶3中。装量不超过烧瓶球容积的1/2为适。关闭拧紧夹6。在水浴锅2内装入适量沸水,接通电炉1加热保温。药液在负压下受热后迅速蒸发,溶媒蒸汽经蒸馏烧瓶的支管进入汽水分离器——贮液瓶14中,复被引入分馏柱——空气净化预热器9内,水份及溶媒的高沸点馏份在分馏柱中冷凝成液体流回贮液瓶14中贮集;溶媒的低沸点馏份被引入冷凝管11中冷凝成液,流入贮液瓶15
In the process of preparation of Chinese herbal injection, solvent recovery is also an important part of the process. This article describes a set of laboratory equipment for the preparation of the hospital room application, but also for factory product research and pharmaceutical teaching reference. First, the structure shown in the drawings. Second, the operation of the vacuum pump 16 is turned on, open the water stop clip 6, through the inlet pipe 7 to be recovered solvent solution to the distillation flask 3. Loading capacity of not more than 1/2 of the flask ball volume is appropriate. Close the clamp 6. Into the water bath 2 into the amount of boiling water, connected to the electric furnace 1 heat insulation. The liquid medicine evaporates rapidly under the negative pressure, and the solvent vapor enters the steam-water separator-liquid storage bottle 14 through the branch pipe of the distillation flask, and is introduced into the fractionation column - the air purification preheater 9, the moisture and the solvent The high-boiling fraction is condensed in a fractionating column to be returned to the liquid storage tank 14 for storage. The low-boiling-point fraction of the solvent is introduced into the condensation tube 11 to be condensed into liquid and flows into the liquid storage bottle 15