巴黎免疫化学和免疫病理实验室J C Brouet等著文:血液病(白血病或肉瘤)的神经症状一般与白血病浸润至神经根或脑膜有关。临床和解剖特征以及在多发性骨髓瘤或巨球蛋白血症所观察到的慢性神经病变的发展,都表明神经症状在生理病理学上不同。最新的研究表明,单克隆免疫球蛋白或由异常淋巴细胞分泌 Paris CCH Immunology and Immunopathology Laboratory J C Brouet et al: Neurological symptoms of hematological disorders (leukemias or sarcomas) are generally associated with leukemia infiltration into the nerve root or the meninges. Clinical and anatomical features, as well as the development of chronic neuropathies observed in multiple myeloma or macroglobulinemia, indicate that neurological symptoms are physiologically and pathologically different. Recent research shows that monoclonal immunoglobulins are secreted by abnormal lymphocytes