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A new derivative of triterpene named Erigeronol 1 was isolated from the EtOH extract of the aerial part of Conyza canadensis together with 15 known compounds for the first time from this plant.The structure of Erigeronol 1 was elucidated as 3-O-(hydroxyacetyl) -23,28-dihydroxy-β-amyrin by hydrolysis and spectroscopic analysis.Erigeronol 1 showed potent cytotoxic activity with IC_(50) value of 7.77±0.47μg/mL against melanoma B16 determined by the 3-(4,5-dimethylthiazo-2-yl)-2,5-diphenyltetrazolium bromide(MTT) method.
A new derivative of triterpene named Erigeronol 1 was isolated from the EtOH extract of the aerial part of Conyza canadensis together with 15 known compounds for the first time from this plant. The structure of Erigeronol 1 was elucidated as 3-O- (hydroxyacetyl) - 23,28-dihydroxy-β-amyrin by hydrolysis and spectroscopic analysis. Erigeronol 1 showed potent cytotoxic activity with IC 50 value of 7.77 ± 0.47 μg / mL against melanoma B16 determined by the 3- (4,5-dimethylthiazo-2 -yl) -2,5-diphenyltetrazolium bromide (MTT) method.