本研究观察了高乌甲素硬膜外腔注射术后镇痛的效能和副作用。患者５０例随机分为５组，Ａ、Ｂ、Ｃ３组为观察组，分别用高乌甲素４ｍｇ、８ｍｇ、１２ｍｇ；Ｄ、Ｅ两组为对照组，分别用生理盐水６ｍｌ和吗啡２ｍｇ，于手术结束时将药液注入硬膜外腔。结果：５组镇痛的疗效和维持时间顺序为Ｅ组＞Ｃ组＞Ｂ组＞Ａ组＞Ｄ组，其中Ｃ组能达到患者有效镇痛的基本要求，其镇痛效能虽不及Ｅ组的吗啡，但无吗啡的不良反应。表明应用高乌甲素行术后镇痛是有效和安全的。 This study looked at the efficacy and side effects of post-injection analgesia with lappaconitine epidural injections. Fifty patients were randomly divided into five groups. Groups A, B and C3 were treated with lappaconitine 4 mg, 8 mg and 12 mg respectively. The rats in groups D and E were treated with saline 6 ml and morphine 2 mg respectively The solution is injected into the epidural space at the end of the procedure. Results: The analgesic efficacy and maintenance time of the five groups were E group> C group> B group> A group> D group, of which C group could meet the basic requirements of effective analgesia in patients and its analgesic efficacy was not as good as that of E group Morphine, but no morphine adverse reactions. Show that the application of lappaconitine postoperative analgesia is effective and safe.