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目的 :探讨诺仕帕片剂治疗肾绞痛、胆绞痛的临床疗效。方法 :对诊断明确的肾绞痛、胆绞痛患者 940例随机分为两组 ,应用诺仕帕片剂与抗胆碱能药 (6 5 4- 2 )口服比较 ,采用电话随访。评价指标 :(1)服药期间有无疼痛复发 ;(2 )疼痛复发时分别增加口服诺仕帕、6 5 4- 2一次 ,疼痛能否缓解或解除。结果 :诺仕帕组疼痛复发率为 2 2 77% ,6 5 4- 2组疼痛复发率为 6 4 2 4%。两组间比较差异有显著意义 (P <0 0 0 5 ) ;疼痛开始时口服效果比较 ,诺仕帕组有效率 86 2 0 % ,6 5 4- 2组有效率 12 73 % ,组间比较差异有显著意义 (P <0 0 0 5 )。结论 :诺仕帕对肾绞痛、胆绞痛有明显的解痉止痛及预防疼痛复发效果。
Objective: To investigate the clinical efficacy of Nuosipa tablet in the treatment of renal colic and biliary colic. Methods: A total of 940 patients with definite diagnosis of renal colic and biliary colic were randomly divided into two groups. The patients were followed up by phone with Nostradal tablet and anticholinergic drugs (654-2) orally. Evaluation indicators: (1) whether there is pain during the medication recurrence; (2) the recurrence of pain were increased oral nostalgia, 6 5 4 2 once, the pain can be relieved or relieved. Results: The recurrence rate of pain in nocexam group was 2 2 77%. The recurrence rate of pain in 6 5 4 2 group was 6 4 2 4%. There was significant difference between the two groups (P <0.05). Compared with the oral effect at the beginning of pain, the effective rate was 86.20% in the group of Nocexan and 12.73% of the effective rate in the group of 65.4-2. Comparing the two groups, The difference was significant (P <0 0 0 5). Conclusion: Nostradas has obvious antispasmodic and analgesic effects on renal colic and biliary colic and prevention of pain recurrence.