美托洛尔属无内源性拟交感活性选择性β_1受体阻滞剂,因具有负性肌力作用,曾被禁用于心力衰竭。新近研究,由于它可上调心肌的β受体密度,降低血中儿茶酚胺及减慢心率等作用,从而改善心功能。我院于1990年12月至1993年4月对20例快速房性心律失常伴心衰患者应用了洋地黄及美托洛尔,现将治疗结果报道如下。 Metoprolol is an endogenous sympathomimetic selective beta-1 blocker that has been banned from heart failure due to its negative inotropic effect. Recent research, because it can upregulate the myocardial receptor density, reduce blood catecholamines and slow down the heart rate and other effects, thereby improving cardiac function. Our hospital in December 1990 to April 1993 on 20 cases of tachyarrhythmia with heart failure patients with digitalis and metoprolol, the treatment results are reported below.