论文部分内容阅读
目的探讨影响子痫前期发病的病因及其相关危险因素,为临床早期防治子痫前期提供依据。方法采用回顾性病例对照研究法,收集92例子痫前期患者作为病例组,同期选择92例正常妊娠的孕妇作为对照组;对两组研究对象进行问卷调查,采用单因素法、多因素Logistic回归法来筛选影响子痫前期发病的相关因素。结果多因素Logistic回归分析结果显示,孕妇年龄(OR=4.259)、高血压家族史(OR=2.852)、子痫前期史(OR=4.855)、妊娠期高血压(OR=6.001)、妊娠期糖尿病或肾病(OR=2.627)、妊娠期尿路感染(OR=2.050)等均为子痫前期发病的危险因素。结论影响子痫前期发病的因素较多,其独立危险因素包括高龄、高血压家族史、子痫前期史、妊娠期高血压、妊娠期糖尿病或肾病,应加强围产期保健,及时治疗妊娠期疾病,根据围产期高危因素采取个体化干预措施,预防和减少子痫前期的发病率。
Objective To explore the etiology and related risk factors affecting the pathogenesis of preeclampsia and provide the basis for prevention and treatment of preeclampsia in the early stage of clinical practice. Methods A retrospective case-control study was conducted in 92 cases of preeclampsia patients as the case group and 92 normal pregnant women as the control group during the same period. The subjects of the two groups were surveyed by questionnaires. Single factor and multivariate Logistic regression To screen the factors that affect the incidence of preeclampsia. Results The multivariate Logistic regression analysis showed that the average age of pregnant women (OR = 4.259), family history of hypertension (OR = 2.852), preeclampsia (OR = 4.855), gestational hypertension (OR = 6.001), gestational diabetes mellitus Or kidney disease (OR = 2.627), urinary tract infection during pregnancy (OR = 2.050) were risk factors for preeclampsia. Conclusion There are many factors influencing the incidence of preeclampsia. The independent risk factors include age, family history of hypertension, preeclampsia, gestational hypertension, gestational diabetes mellitus or nephropathy. We should strengthen perinatal care and timely treatment of pregnancy Disease, according to the risk factors of perinatal individual interventions to prevent and reduce the incidence of preeclampsia.