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目的:探究老年膀胱癌相关多原发癌患者的临床特点。方法:回顾性分析2010年1月-2012年6月期间,我院收治的42例老年膀胱癌相关多原发癌患者的临床资料。结果:42例患者全部经过病理检查,其中老年膀胱癌相关多原发癌发生于消化系统的患者10例,泌尿系统的患者18例,生殖系统患者4例,呼吸系统患者6例,其他系统患者4例。异时性患者24例,其中22例经第一癌对症治疗后生存54-145个月,2例死亡;同时性患者18例,其中10例经对症治疗后生存3.5-47个月,8例死亡。同时性与异时性患者的累计生存率之间具有明显的统计学差异,差异具有统计学意义,(P<0.05),肿瘤分期和生存率之间的关系密切,具有统计学意义(P<0.01)。结论:近年来,老年膀胱癌相关多原发癌的发病几率明显上升,其中主要表现为呼吸系统、消化系统和泌尿系统,而同时性老年膀胱癌相关多原发癌患者的生存率低于异时性患者,肿瘤分期越高,预后越差,对患者进行尽早的诊断和治疗对于提高患者的生存率意义重大。
Objective: To investigate the clinical features of multiple primary cancer associated with bladder cancer in the elderly. Methods: The clinical data of 42 elderly patients with multiple primary bladder cancer associated with primary cancer admitted to our hospital from January 2010 to June 2012 were analyzed retrospectively. Results: All the 42 patients were pathologically examined. Among them, 10 cases of multiple primary cancer related to bladder cancer occurred in the digestive system, 18 cases of urinary system, 4 cases of reproductive system, 6 cases of respiratory system and 6 cases of other system patients 4 cases. Twenty-four patients with heterochronous disease, including 22 patients after the first cancer symptomatic treatment of survival 54-145 months, 2 deaths; simultaneous patients in 18 cases, of which 10 patients survived after symptomatic treatment 3.5-47 months, 8 patients death. There was a statistically significant difference between the mean and cumulative survival rates of patients with synchronous and synchronous, the difference was statistically significant (P <0.05), the correlation between tumor stage and survival rate was statistically significant (P < 0.01). Conclusion: In recent years, the incidence of multiple primary cancers associated with bladder cancer in elderly patients increased significantly, of which the respiratory system, digestive system and urinary system were mainly manifested, while the survival rate of patients with multiple primary cancers associated with bladder cancer at the same time was lower than that of patients with multiple primary cancers Time-related patients, the higher the stage of the tumor, the poorer the prognosis, the patient’s early diagnosis and treatment for improving the survival rate of patients is significant.