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作者考查123例新诊断、未经化疗的急性淋巴细胞白血病(ALL)儿童的血清谷丙转氨酶(SGPT)活性,研究其能否作为肝脏受累的指标和预测患者预后的参数。患儿中数年龄为4.8岁(2月-15岁),男61例,女62例。平均随访69月(22-140月)。在化疗前测定SGPT和血清谷丙转氨酶(SGOT)活性,二者的正常值上限均为40IU/L。测定结果发现:123例患儿中数SGPT活性为14IU/L,有13例(9%)患儿
The authors examined serum glutamate-pyruvic transaminase (SGPT) activity in 123 children with newly diagnosed and untreated acute lymphoblastic leukemia (ALL) and studied whether they could be used as indicators of liver involvement and predict patient outcomes. The median age of children was 4.8 years (February -15 years), 61 males and 62 females. The average follow-up period was 69 months (22-140 months). The SGPT and serum glutamic-pyruvic transaminase (SGOT) activity were measured before chemotherapy, and the upper limit of the normal value of both was 40 IU/L. The results showed that the median SGPT activity in 123 children was 14 IU/L and 13 children (9%) had children