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目的明确诊断并分析1例新生儿疑似流行性脑膜炎死亡病例可能的传染来源和传播途径。方法收集死亡病例的血液标本及其密切接触者的咽试子标本并进行菌株的分离培养和分型及药敏试验。结果死亡病例的血标本及其密切接触者患儿父亲咽试子标本均分离到B群脑膜炎奈瑟菌菌株,2株菌株对氨苄西林、环丙沙星、利福平、氯霉素、头孢噻吩、红霉素及四环素均敏感,对磺胺类药耐药。结论根据该病例的特点和实验室检测结果,判断该病例为B群脑膜炎奈瑟菌引起的死亡病例。
Objective To clearly diagnose and analyze the possible sources of infection and transmission of a neonatal suspected meningitis meningitis. Methods Blood specimens of deaths and their pharyngeal specimens from close contacts were collected and the strains were isolated, cultured, classified and susceptible. Results The Neisseria meningitidis group B strains were isolated from the blood samples of the dead cases and the pharyngeal samples of their close contacts. Two strains were positive for ampicillin, ciprofloxacin, rifampin, chloramphenicol, Cephalothin, erythromycin and tetracycline are sensitive to sulfa drug resistance. Conclusion According to the characteristics of the case and laboratory test results, the case was determined to be Neisseria meningitidis group B deaths.