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目的:探讨照射早期胎鼠对成年小鼠学习与记忆的长期效应。方法:①用60Coγ射线0.25~1.5Gy(剂量率为1Gy/min)照射妊娠14d的瑞士小鼠腹部,待其分娩的幼仔饲养至6个月或12和18个月时进行试验。②将小鼠放入孔板箱的中央进行孔板试验,观察5min内小鼠口鼻
Objective: To investigate the long-term effects of early embryo irradiation on learning and memory in adult mice. Methods: (1) Irradiation was given to the abdomen of Swiss mice 14 days pregnant with 60Coγ ray 0.25 ~ 1.5Gy (dose rate 1Gy / min), and their childbirth was fed until 6 months or 12 and 18 months . ② The mice were placed in the center of the orifice plate plate test to observe the mice nose and mouth within 5min