目的：探讨照射早期胎鼠对成年小鼠学习与记忆的长期效应。方法：①用６０Coγ射线０．２５～１．５Gy（剂量率为１Gy／min）照射妊娠１４d的瑞士小鼠腹部，待其分娩的幼仔饲养至６个月或１２和１８个月时进行试验。②将小鼠放入孔板箱的中央进行孔板试验，观察５min内小鼠口鼻 Objective: To investigate the long-term effects of early embryo irradiation on learning and memory in adult mice. Methods: (1) Irradiation was given to the abdomen of Swiss mice 14 days pregnant with 60Coγ ray 0.25 ~ 1.5Gy (dose rate 1Gy / min), and their childbirth was fed until 6 months or 12 and 18 months . ② The mice were placed in the center of the orifice plate plate test to observe the mice nose and mouth within 5min