肺纤维化是一组以肺间质弥漫性渗出、浸润和纤维化为主要病变的疾病。其病因复杂 ,预后极差 ,临床上缺乏有效的治疗手段 ,并且许多治疗方法具有严重的副作用 ,其 5年生存率仅 5 0 % [1 ] 。近年来随着对肺纤维化的发病机理的深入研究 ,使之在治疗上取得了相当的进展。现将近年 Pulmonary fibrosis is a group of diseases characterized by diffuse exudation, infiltration and fibrosis of the lung as the main lesion. Its complex etiology, poor prognosis, clinical lack of effective treatment, and many of the treatment has serious side effects, the 5-year survival rate was only 50% [1]. In recent years, with the pathogenesis of pulmonary fibrosis in-depth study, so that treatment has made considerable progress. Now in recent years