喉疣状癌较少见,诊断比较困难,是分化好的鳞癌的变异,占鳞癌的1～2%,个别报告占11%,高龄男性多见。症状与其他喉癌相似,病程长,肿物可生长相当大以致呼吸困难及吞咽困难而无转移,50%好发在声门部,约20～30%发生在声门上,肿物呈乳头状突出,表面灰白色;显微镜下应注意与角化症、乳头瘤、原位癌及分化良好的鳞癌相鉴别。本文复习了有关喉疣状癌文献并报告两个病例。病例1:男性,70岁,声嘶一个月,有多年吸烟史。间接喉镜检查见有白色乳头状增生,侵及右侧声带全长并越过前联合达左侧声带前半部,颈部未触及肿大淋巴结。喉断层拍片声门下未见肿物。组织学检查可见上皮角化增生,结缔组织下有淋巴细胞浸润。6周后,再次活检与临床相结合诊断为疣状癌。于内窥镜下取尽残余肿 Throat-like carcinoma is rare and difficult to diagnose. It is a variation of well-differentiated squamous cell carcinoma, accounting for 1-2% of squamous cell carcinomas, and individual reports account for 11%. Older males are more common. Symptoms Similar to other laryngeal cancers, the disease duration is long, the masses can grow so large that breathing difficulties and dysphagia without metastasis, 50% occur in the glottis, about 20 to 30% occur in the glottis, and the mass is nipple Prominent, gray surface; under the microscope should pay attention to keratosis, papilloma, carcinoma in situ and differentiated squamous cell carcinoma. This article reviewed the literature on laryngeal carcinoma and reported two cases. Case 1: Male, 70 years old, snoring for one month, smoking history for many years. Indirect laryngoscopy showed white papillary hyperplasia, invading the entire length of the right vocal cords and crossing the anterior to the anterior half of the left vocal cords, and the necks did not touch the enlarged lymph nodes. There was no mass under the glottic flap. Histological examination showed epithelial hyperkeratosis, lymphocytic infiltration under connective tissue. After 6 weeks, another biopsy was combined with clinical diagnosis of verrucous carcinoma. Remove residual swollen endoscope