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目的：观察欣母沛（卡前列素氨丁三醇注射液）用于预防和治疗剖宫产患者因宫缩乏力所致产后出血的临床疗效。方法选择2010年2月～2012年2月具有剖宫产指征且有产后出血高危因素的孕妇106例，随机分2组：50例观察组为缩宫素联合欣母沛给药患者，56例对照组为采用缩宫素单独给药患者。观察两组患者剖宫产后2h、24h平均出血量，计算产后出血率，对两组结果进行统计分析。结果观察组产后出血发生率明显少于对照组，产后2h、24h平均出血量均明显减少，差异有统计学意义（P＜0.05）。结论欣母沛可有效控制宫缩乏力性产后出血，疗效优于缩宫素，且具有安全、高效、迅速、方便等特点。“,”Objective To observe the clinical effect of Hemabate in prevention and treatment of uterine atonic postpartum hemorrhage during cesarean section. Methods From February 2010 to February 2012, 106 cases of pregnant women with high hemorrhagic risk factors and cesarean section indication were randomly divided into 2 groups:observation group(injected with oxytocin and Hemabate, n=50), and control group(injected with only oxytocin,n=56).The bleeding amount within 2h and 24h after cesarean delivery and incidence of postpartum hemorrhage were compared between the two groups. Results The bleeding amount within 2h and 24h after cesarean delivery and the incidence of postpartum hemorrhage in the observation group were both much less than those in control group. Conclusion Hemabate is effective for prevention and treatment of postpartum hemorrhage. Its curative effect is better than that of oxytocin, which is safe, efifcient, fast and convenient.