论文部分内容阅读
组织黑色素着色为一种来源于神经外胚的特殊细胞的分泌活动所致,这种细胞名为黑素细胞,位于表皮与真皮交界处、毛囊及眼色素层。黑色素本身为一种蛋白结合色素,主要为吲哚单体的不同程度氧化,并且在黑素细胞胞浆内的一种奇特小器官即黑素体内所合成。肿瘤内含有异常黑素细胞、具有浸润性者名为恶性黑色素瘤,其色素的产生及酪氨酸的代谢各不相同。根据这种肿瘤的电子显微镜观察可看出两种不同的黑素体。A型肿瘤的黑素体呈雪茄烟形,其前黑素体内呈螺旋线结构;B型肿
Tissue melanin pigmentation is caused by a secretory activity of specialized cells derived from neuroectodermal cells called melanocytes, located at the junction of the epidermis and the dermis, the hair follicles, and the pigment layer of the eye. Melanin itself is a protein-binding pigment that is primarily oxidized to a varying degree by the quinone monomer and is synthesized in a peculiar, small organ called melanin within the cytoplasm of melanocytes. Tumors containing abnormal melanocytes and those with invasiveness are called malignant melanomas, and their pigment production and tyrosine metabolism are different. According to electron microscopic observation of this tumor, two different melanosomes can be seen. The melanosomes of type A tumors are cigar-shaped, with a helix in the anterior melanin structure; B-type tumors