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目的：探讨了卵巢癌患者手术治疗前后血清CA50.cA125和HCY水平的变化及意义。方法应用放射免疫分析法和免疫化学法对33例卵巢癌患者进行了手术治疗前后血清CA50.cA125和HCY检测，并与35名正常人作比较。结果卵巢癌患者在手术治疗前血清CA50.cA125和HCY水平均非常显著地高于正常人（P0.05）血清C A50水平与c A125和H C Y水平呈显著正相关（r=0.6014.0.5982. P<0.01）。结论检测卵巢癌患者血清cA50、cA125和HCY水平的变化可有助于对病情的严重程度、病情的发展做出判断。“,”Objective :To explore the clinical Significance of changes of Seran cA50、cA125 and HCY levels in postoperative with ovary cancer.Methods : Seran cA50、cA125(with RIA).Seran HCY (with immune chemistry method)levels were measclked in 33 patients with ovary cancer and 35 Controls.Result : Before operation, the Seran cA50, cA125 and HCY Levels were significantly higther than those in controls (p0.05). Seran cA50 levels were positivelycorrelated with Seran cA125 and HCY levels (r=0.6014, 0.5982, p<0.01). Conclusions: changes of helpful to judge the progression and severity in patients with ovary cancer.